RGB Medical Devices S.A. was founded in 1988 as a University spin-off.RGB is at the forefront of biomedical instrumentation with strong orientation towards research and innovation in Medical Equipment for Operating Rooms and Intensive Care Unit. Developed products cover Vital Signs Monitoring and Infusion Pumps sectors. It is an ISO 13485 compliant, and all products are CE marked in accordance to regulations. More recently RGB has completed FDA 510(k) for some products.

The initial objective of the company was in the development of advanced medical devices and consultancy in the area of Bioengineering. Amongst the different pioneering devices manufactured by the company is the Baricontrol. This device was designed for B.Braun Infusion pumps Manufacturer to be used in clinical operations and intensive care units for arterial blood pressure regulation with an automatic dosification of vasoactive drugs; it became in 1992 the first robotic device to provide automated medical assistance, with comparable and stable performance as compared to trained medical personnel.

Since 1995, RGB has moved into the Vital Signs Medical field with a wide range of vital signs multi-parameter monitors called Omicrom VISION.The first model was launched in the Interhospital9́5 exhibition in Hannover. SAFE21 was the first CE marked multi-parameter remote monitor as a core component to home care in a telemedicine service.